Increased work thrown on to a tissue may produce hypertrophy, but, if this excessive function be kept up, atrophy will follow; even the blacksmith's arm breaks down owing to the hypertrophic muscle fibres becoming markedly atrophied.
He was a descendant of one of the founders of the New Haven colony, worked as a boy in an uncle's blacksmith shop and on his farm, and in 1797 graduated from Yale, having studied theology under Timothy Dwight.
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